YIpub

  • Publications
  • Invited Speaker
  • Invited Lecture
  • 日本語総説
  • 国内シンポジウム、学会発表、講演会
  • 2015

    72. Yuyama K. and Igarashi Y. (2015). Function of ganglioside and sphingolipid-linked exosome secretion in sequestering Alzheimer's amyloid-β. 56th ICBL, Invited lecture (Iguazu, Argentina, September 22-26).

    71. Igarashi Y. and Yuyama K. (2015). A potential function of secreted exosomes in sequestering Alzheimer's amyloid-β peptide. Nuerological Diseases Summit, Invited speaker (San Francisco, July 6-9).

    70. Igarashi Y. (2015). Sphingolipid biology and sphingolipid-related drug and functional food development : 30 years study in USA and in Japan. 10th Sphingo Therapy Conference, Prenary lecture (Kanazawa, Japan, June 16-18).

    69. Igarashi Y. and Yuyama K. (2015). Function of ganglioside and sphingolipid-linked exosome secretion in sequestering Alzheimer amyloid-β. International Ceramide Conference, Invited speaker (Izmir, Turkey, May 6-10).

    68. Igarashi Y. and Sakai S. (2015). Sphingolipid biology and drug and functional food development. SLING Workshop:Chemical diversity of sphingolipids and their potential biological functions, Invited speaker (Singapore, March 26-27).

    2014

    67. Igarashi Y. (2014). Roles of sphingolipid metabolites on metabolic syndrome, Altzheimer disease and skin health. Korean Lipid Biology Symposium, Invited speaker (Seoul, July 11).

    66. Igarashi Y. (2014). Neuronal exosomes in clearance of Alzheimer amyloid proteins and regulatory roles of sphingo(glyco)lipids. 5th International Singapore Lipid Symposium, Invited speaker (Singapore, March 15).

    2013

    65. Igarashi Y. and Yuyama K. (2013). Neuronal exosomes can eliminate Alzheimer's amyloid protein in vitro and in vivo model mouse. BIT's 4th world gene Convention-2013, Invited speaker (Haikou, November 15).

    64. Igarashi Y., Sun H. and Yuyama K. (2013). Exosomal sphingolipids responsible for the clearance of Alzheimer’s amyloid. ISN-ASN SATELLITE SYMPOSIUM, Invited Speaker (Cancun, April 17-19).

    2012

    63. Mitsutake S., Zama K., Yoshida T., Takemoto H., Okazaki T. and Igarashi Y. (2012). SMS2 is implicated as a novel regulator of lipid microdomain structure and function. Gordon Research Conference: Glycolipid and Sphingolipid Biology, Invited Speaker (Italy, April 22-27).

    2011

    62. Igarashi Y. (2011). Role sphingomyelin in lipid droplet formation in liver and obesity. The 2nd Chinese Lopid Biochemistry Meeting, Invited speaker (Beijing, October 31-November 1).

    61. Mitsutake S. and Igarashi Y. (2011). Sphingomyelin synthase 2 is responsible for obesity and lipid droplet formation in liver and is a novel regulator of membrane microdomain. 52st ICBL Conference Invited speaker (Warsow, Poland, August 30-September 3).

    60. Igarashi Y. (2011). Regulation of Sphingolipid Metabolism in Human Health. BIT 1st Annual World Congress of Molecular & Cell Biology (Beijing, August 8-9).

    59. Igarashi Y., Mitsutake S. and Yuyama K. (2011). Roles of sphingolipid metabolism in lipid droplet formation in liver and exosome formation in neuronal cells. 30th Naito Conference, Invited speaker (Sapporo, Japan, June 28-July 1).

    58. Igarashi Y. (2011). A new challenge in sphingolipid biology: lipid signaling to lipid dynamics. UNIST Symposium: Recent Trends in Lipid Research, Invited speaker (UNIST, Ulsan, Korea. January 7).

    2010

    57. Igarashi Y. (2010). Ceramide metabolism and membrane dynamics 51st ICBL Conference Invited speaker (Bilbao, Spain, September 7-12).

    56. Mitsutake S., Mizutani Y., Yuyama K. and Igarashi Y. (2010). Through lipid signaling to lipid dynamics: a new challenge in sphingolipid biology. 27th Naito Conference Chair, Invited speaker (Sapporo, Japan, June 29-July 2).

    2009

    55. Igarashi Y., Mizutani Y., Mitsutake S. and Kihara A. (2009). Ceramide metabolism and signaling in the skin. Bioactive Lipids Conference (Cancun, Mexico, October 25-28).

    54. Kihara A. and Igarashi Y. (2009). Synthesis of very long-chain fatty acid and its relationship to sphingolipid metabolism. 50th ICBL Conference (Regensburg, Germany, September 1-6).

    53. Igarashi Y. (2009). Ceramide biosynthesis in keratinocyte and iys role in skin Function. 5th Charleston Ceramide Conference (Charleston, NC, March 11-14).

    2008

    52. Igarashi Y. (2008). Ceramide metabolism and functions in the skin-an expectation to photo-imaging studies-. Imaging-Luminescent and Fluorescent Probing Technology Ⅱ, Invited speaker (Hokkaido Univ., Sapporo, November 7).

    51. Igarashi Y. (2008). Ceramide Synthesis in Keratinocyte by Ceramide Synthase Family: Enzymatic Basis for the Preference of Fatty Acid Chain Length and Hydroxylation, 5th Lipidomics Meeting- Lipids for the Future: From Agroresources to Human Health(France, October 21-23).

    2007

    50. Igarashi Y., Kihara A. and Ikeda M. (2007). Topological metabolism and transbilayer dynamics of sphingolipids. 2nd Conference Phosopholipase and other lipid mediators, Invited speaker (Sorento, Italy, May 9-12).

    49. Igarashi Y., Ikeda M. and Kihara A. (2007). Topological metabolism and transbilayer dynamics of sphingolipids. Japan-Swiss Seminar, Invited Speaker (Tsukuba, Japan, February 27-March 2).

    48. Igarashi Y. (2007). Openning Remark and Introduction: Learning from Dr. Hakomori. Glycobiology and Sphingobiology 2007 -Hakomori Commemorative International Forum (Tokushima, February 28-March 2).

    2006

    47. Igarashi Y., Kohno T. and Kihara A. (2006). Regulation of cell signaling of sphingosine1-phosphate through G-protein coupled receptors. FAOPS 2006, Iinvited speaker (Seoul, Korea, October 15-17).

    46. Kihara A., Ohno Y. and Igarashi Y. (2006). Protein acyltransferases involved in the palmitoylation of sphingosine 1-phosphate-related enzymes. FASEB Summer Research Conference, Protein lipidation, signaling and membrane domain, Invited speaker (Indian wells, CA, July 22-27)

    45. Igarashi Y., Kihara A. and Ikeda M. (2006). Metabolic topology and trans-bilayer movement of sphingoid long-chain base. Gordon Conference on Sphingo/glycolipid Biology, Invited speaker (Ventura, CA, January 8-13).

    2005

    44. Igarashi Y., Kim T.J. and Mitsutake S. (2005). Ceramide kinase is required for degranulation pathway in mast cell and regulated by Calmodulin/Ca2+ and PIP2 through specific interaction with their recognition domains. FEBS-IUMBM, 2005 (Budapest, Humgary, July 2-7).

    43. Uemura S., Kihara A. and Igarashi Y. (2005). Membrane Topology of Yeast Mannosylinositol Phosphorylceramide (MIPC) Synthesis by Two Distinct Mannosyltransferases, Csg1 and Csh1, Interacting with Csg2p Japan-Netherland Joint seminar (Utrecht, Hoalland, April 18-20).

    2004

    42. Igarashi Y. (2004). Physiological roles of sphingolipids and its colorful world. Otsuka International Summer Seminar for Lipid-mediator and Glycobiology (Tokushima, Japan, August 2).

    41. Kihara A. and Igarashi Y. (2004). Yeast genetic approaches for studying the dynamics and signaling functions of sphingo/glycolipids, including lipid microdomain formation. A satellite meeting of the International and Asia-pacific Sociaties fro Neurochemistry (Academia Sinica, Taipei, Taiwan, February 8-11).

    2003

    40. Ikeda Y., Kihara A. and Igarashi Y. (2003). Regulation of S1P lyase. Charleston Ceramide Conference (Como, Italy, July).

    39. Mitsutake S. and Igarashi Y. (2003). Ceramide kinase is involved in degranuation pathway rat basophilic leukemia (RBL-2H3) cells. Charleston Ceramide Conference (Como, Italy, July).

    38. Igarashi Y. (2003). Regulation of S1Pcontent by sphindosine kinases, S1Pphosphatases, and S1P lyase. FASEB Summer Conference (Aspen,USA, June 30-July 4).

    37. Igarashi Y. (2003). Biological functions of sphingosine 1-phosphate, a platelet derived bioactive lipid. 6th International Conference of Endothelome, Invited Speaker (Otaru, Japan, February 12).

    36. Igarashi Y. (2003). Roles of N-terminal glycosylation and procession in S1P receptors in lignad-induced internalization. 6th international symposium on biochemical roles of eukaryotic cell surface macromolecules, Invited speaker (Kollata, India, January 16-18).

    35. Igarashi Y. (2003). N-glycans of sphingosine 1-phosphate receptor regulate ligand-induced receptor internalization. XVII International Symposium on Glycoconjugates, Invited speaker (Bangalore, India, January 12-16).

    2002

    34. Igarashi Y. (2002). Functions of a platelet-derived lipid mediator sphingosine 1-phopsphate and its receptors-A new era of sphingolipid biology. 02 Annual meeting of Korean Society of Medical Biochemistry and Molecular Biology, Invited prenary lecture (Seoul, Korea, October 24-26).

    33. Kihara A. and Igarashi Y. (2002). Topological analysis of sphingoid base 1-phosphate phosphatases and identification of transporter protein responsible for resistance for spphingoid bases in yeast. 43th ICBL Conference (Graz, Austria, Sepember 11-14)

    32. Yu Fukuda. and Igarashi Y. (2002). PECAM-1 as a SPHK association protein. Gordon Conference on "Sphingolipid and Glycolipid Biology" (Ventura, CA, January 27-31).

    31. Kihara A. and Igarashi Y. (2002). Topological analysis of sphingoid base 1-phosphate phosphatases and identification of transporter protein responsible for resistance for spphingoid bases in yeast. Gordon Conference on " Sphingolipid and Glycolipid Biology" (Ventura, CA, January 27-31).

    2001

    30. Inokuchi J., Tagami S., kabayama K., Yoshimura H., Kitamura F., Uemura S., Ogawa C., Ishii A., Saito M., Ohtsuka Y., Fujiwara Y., Igarashi Y. and Kawakami Y. (2001). Ganblioside GM3 participates in the pathological conditions of insulin resistance. 2001 Glycobiology Conference (Boston, November 13-17).

    29. Tukahara T. and Igarashi Y. (2001). A novel sphingosine kinase from human platelets. Takeda 1st PharmaScience Conference "Lipid mediators and related diseases" (Hilton Tokyo, Japan, October 3-5).

    28. Sano T., Kihara A., Wada A., Tigyi G. and Igarashi Y. (2001). Production of LPA in platelets. Takeda 1st PharmaScience Conference" Lipid mediators and related diseases" (Hilton Tokyo, Japan, October 3-5).

    27. Igarashi Y. (2001). Intorductory comments on lysophospholipid mediators. Opening remarks in the session of lysophospholipid mediators in Takeda 1st PharmaScience Conference "Lipid mediators and related diseases" (Hilton Tokyo, Japan, October 3-5).

    26. Igarashi Y. (2001). Production, Secretion, and Functions of a Lipid Mediator Sphingosine 1-phosphate in the Blood. Invited lecture in 7th international Conference of PAF and other lipid mediators (Tokyo, Japan, September 24-26).

    25. Igarashi Y. (2001). Production, Secretion, and Functions of a Lipid Mediator Sphingosine 1-phosphate in the Blood. Invited lecture in satelite Symposium on Sphingolipid Biology (Iguazu Falls, Argentina, August 23-26).

    24. Igarashi Y. (2001). "Platelet functions and effect of Sphingosine 1-phosphate". Invited lecture in FASEB Summer Conference of Lysophospholipids and Related Bioactive Lipids in Biology and Diseases (Tucson, Arizona, June 9-14)

    23. Igarashi Y., Yatomi Y. and Tigyi G. (2001). "Production and function of a lipid mediator, sphingosine 1-phosphate in blood, a comparison with lysophosphatidic acid. 42th ICBL Conference, Invited lecture (Belgen, Norway, June 5-9).

    22. Inokuchi J., Kabayama K., Uemura S. and Igarashi Y. (2001). "Bidirectional regulation of integrin functions and tumorigenicity by sialylation and sulfation of lactosylceramide" Japan-Swiss Les Diablerets Conference. (Les Diablerets, Swissland, March 10-12).

    1999

    21. Igarashi Y. (1999). Regulatory mechanism of cell motility by sphingosine 1-phosphate through Edg receptors. International Riken Forum: Glycobiology and Sphingolipid Biology (Wako, Japan, October 13-14).

    20. Wada A., Motohashi K. and Igarashi Y. (1999). Signaling cascade through Edg family sphingosine 1-phophate receptors. New frontier of glyco- and lipid-biology toward the twentyfirst century (Tokushima, Japan, August 28-30).

    19. Yamamura S., Hakomori S., Wada A. and Igarashi Y. (1999). Sphingosine1-phosphate inhibits haptotactic motility by overproduction of focal adhesion site in B16 melanoma cells through Edg-induced activation of Rho. NYAS Synposium "Lysosphingolipids and eicosanoids in cancer and in cardiovascular and neurodegenerative disieses" (New York, USA, June 25-28).

    18. Igarashi Y. (1999). Regulatory mechanism of cell motility by sphingosine 1-phosphate through Edg receptors. Riken Forum: Glycobiology and Sphingolipid Biology (Wako, Japan, October 13-14).

    1998

    17. Igarashi Y. (1998). Sphingosine 1-phosphate as an intercellular messenger released from activated platelets, conceivably playing a variety of physiological and pathophysiological roles in blood vessels. Gordon Conference on "Sphingolipid and Glycolipid Biology" (Ventura, CA, January 11-16).

    1997

    16. Igarashi Y. and Yatomi Y. (1997). Sphingosine 1-phosphate is a blood constituent released from activated platelets, possibly playing a variety of physiological and pathophysiological roles. International Symposium on structure, metabolism and functions of glycosphingolipids and sphingolipids (Warsaw, Poland, September 4-6).

    15. Igarashi Y. and Yamamura S.(1997). Sphingosine 1-phosphate regulates melanoma cell motility through a receptor-coupled extracellular action and in a pertussis toxin insensitive manner. IUBMB Satellite Symposium " Sphingoglycolipids as mediators of molecular events" (Napa Valley, CA, August 22-24).

    14. Igarashi Y. (1997). Sphingosine 1-phosphate as an intercellular signaling molecule. ASN/ISN Satellite symposium on "Sphingolipids as signaling modulators in the nervous system" (New York, July 13-16).

    1996

    13. Igarashi Y. (1996). Mechanism of apoptosis induction by sphingosine, N,N-dimethylsphingosine, and epidermal growth factor in solid tumor cells: A possible involvement of mitogen-activated protein kinase in apoptotic signaling. Gordon Conference on "Structure and biological function of Glycolipids and sphingolipids" (Gifu, Japan, September 29-October 4).

    12. Igarashi Y. (1996). The roles of sphingosine-1-phosphate in platelet function and their regulation by methylsphingosine. 7th meeting on Development of New Methodology in Platelet Function Measurement (Tokushima, Japan, March 16).

    1995

    11. Igarashi Y.(1995). Induction of apoptosis by sphingosine, N,N-dimethylsphingosine, and EGF in solid tumor cells: a possible involvement of MAP kinase cascade in apoptotic signaling. '95 Chicago Neurosurgery Center (CNC) Symposium (Chicago, IL, October 18-20).

    10. Hakomori S. and Igarashi Y. (1995). Role of sphingoglycolipids in signal transduction, and their medicinal application for control of tumor progression and inflammatory processes. AIMECS 95 (Tokyo, Japan, September 3-6).

    9. Igarashi Y., Yatomi Y., Yamamura S., Ruan F. and Hakomori S. (1995). Sphingosine-1-phosphate acts as an intercellular but not intracellular messenger in platelet activation and cell motility inhibition. 13th International Symposium on Glycoconjugates (Seattle, WA, USA, August 20-26). Glycoconjugate J. 12: 579.

    8. Igarashi Y. (1995). Biological functions of sphingosine-1-phosphate in various types of cell motility and platelet activation. Gordon Conference on"Structure and biological function of Glycolipids and sphingolipids" (Ventura, CA, January 15-20).

    1994

    7. Singhal A.K., Igarashi Y. and Hakomori S. (1994). Role of cell membrane carbohydrates in cancer. Tohoku International Symposium on Breast Cancer (Sendai, Japan, September 25-28).

    1993

    6. Igarashi Y., Sadahira S., Yamamura S. and Hakomori S. (1993). Inhibition of mouse B16 melanoma cell motility by sphingosine-1-phosphate. 3rd international conference on eicosanoids and other bioactive lipids in cancer inflammation and radiation injury (Washington DC, October 12-16).

    5. Hakomori S. and Igarashi Y. (1993). Control of transmembrane signaling by ganglioside and sphingolipid derivatives. 34th international conference on the biochemistry of lipids (The Netherlands, August 25-28).

    1992

    4. Igarashi Y. (1992). Biological function of N-methyl sphingosine, sphingosine-1-phosphate, and plasmalopsychosine. Gordon Conference " Glycolipids and sphingolipids" (Hawaii, November 15-20).

    3. Igarashi Y. (1992). Sphingolipids as modifiers of transmembrane signaling: Application to cancer and inflammation. CNC 1992 symposium (Chicago, IL, October 15-17).

    1990

    2. Igarashi Y. and Hakomori S. (1990). Role of ganglioside and its catabolite in the modulation of transmembrane signal transduction. Glycoconjugate J. 7(5): 393.

    1. Igarashi Y. and Hakomori S. (1990). The role of GM3, lyso-GM3 and dimethylsphingosine (DMS) as lipid modulator of transmembrane signaling. in J. Develop Neurosci. Abstracts of the 8th Biennial meeting of the ISDN: pp. 50 (Bal Harbor, FA , June 16-22)